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Anterograde transport of axonal mitochondria is critical for the maintenance of the mitochondria pool and neuronal health. Youjun Wu, Marc Hammarlund (Yale School of Medicine) and colleagues show that the endogenous kinesin-1 and RIC-7 localize at the leading end of mitochondria to drive axonal anterograde transport in vivo in C. elegans. https://hubs.la/Q02p5tD60 | Journal of Cell Biology
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Live imaging of axonal transport.. Live imaging of axonal transport of Nmnat2-Venus in explanted tibial nerve from transgenic mice. Three labelled axons are shown, each with bidirectional trafficking of labelled Nmnat2, a protein with a critically important role in axon survival . (Stefan Milde, Michael Coleman, The Babraham Institute) | Physiotherapy DPT
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jove.com
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