Applied Clinical Trials Online
In the TAK-861-2001 Phase IIb study, oveporexton significantly improved wakefulness, daytime sleepiness, and cataplexy frequency in patients with narcolepsy type 1, outperforming current …
MIRASOL Trial Shows Elahere Significantly Improves Survival in …
Mar 17, 2025 · Results from the Phase III MIRASOL trial (NCT04209855) show that Elahere (mirvetuximab soravtansine-gynx) produced a significant improvement in progression-free …
The Strategic Emergence of Site Networks in Clinical Research
Oct 14, 2024 · These attributes can help sponsors assess the potential of a site or network to meet the specific needs of their trials. For example, a site with a robust infrastructure and …
Phase III Trials Confirm Remibrutinib Effectively Reduces Chronic ...
Mar 6, 2025 · Phase III REMIX-1 and REMIX-2 trials demonstrated that remibrutinib, an oral BTK inhibitor, significantly reduced chronic spontaneous urticaria symptoms in patients …
Interventional vs. Non-interventional Study Classification in the EU ...
On April 16, 2014, the European Parliament and the Council on clinical trials on medicinal products for human use repealed clinical trials Directive 2001/20/EC and adopted a new …
Phase III Trial Data Show Subcutaneous Pembrolizumab as …
Mar 31, 2025 · Subcutaneous administration of pembrolizumab with chemotherapy demonstrated a nearly 50% reduction in patient chair and treatment room time while maintaining efficacy and …
SOUL Trial Shows Oral Semaglutide Significantly Reduces …
Apr 3, 2025 · Results from the Phase III SOUL trial (NCT03914326) published by The New England Journal of Medicine show that treatment with daily oral semaglutide produced a …
Phase III Trials Show Long-Term Efficacy of Cobenfy Treating …
Nov 1, 2024 · Data from a pair of Phase III trials presented at the 2024 Psych Congress demonstrate that Cobenfy (xanomeline and trospium chloride) maintained long-term efficacy in …
Clinical Trial Failure: A Data-Driven Perspective on Risk Mitigation
Apr 14, 2025 · What constitutes clinical trial failure is a matter of perspective. For sponsors, the loss of time and resources when an invested drug fails to reach the market may make the trial …
Genmab’s Rinatabart Sesutecan Continues Success in Advanced …
Mar 17, 2025 · Genmab has shared positive results from the Phase I/II RAINFOL-01 clinical trial showing that its rinatabart sesutecan (Rina-S), an investigational folate receptor-alpha (FRα) …