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  1. Single cell analysis of desiccation induced changes in cornea …

    This study evaluates the hypothesis that dry eye alters the percentages and transcriptional profiles of immune cell populations in the cornea. Methods: Desiccating stress (DS) induced …

  2. Genetic and transcriptional instability alters cancer cell line drug ...

    Consistent with this hypothesis, we found evidence of extensive clonal diversity across widely used compendia of cancer cell lines. We therefore performed comprehensive genetic and …

  3. Single-cell regulomes of human peripheral blood innate lymphoid …

    We anticipate our work to be a starting point to facilitate hypothesis-driven studies in patients, without the need to perform single cell OMICs using precious patients’ material.

  4. Plasticity of epididymal adipose tissue in response to diet-induced ...

    The data provide a powerful resource for future hypothesis-driven investigations of the mechanisms of adipocyte differentiation and adipose tissue plasticity.