The appearance of fever is associated with the release in the hypothalamus of a lipid compound called prostaglandin E2 (PGE2), which has an important role in the regulation of body temperature.

This research can help us to better tailor strategies for managing both body temperature regulation and hydration during heat exposure in older adults. For example, because of reductions in thirst and ...

The regulation of thirst and maintenance of body fluid homeostasis are critical processes for survival, orchestrated by an intricate network of neural and molecular mechanisms. The brain continuously ...

This lesson plan teaches students how the human body self-regulates to maintain a stable internal environment despite changes in the external environment -- a process called homeostasis. Most of the ...

Dear Dr. Roach: I am an 80-year-old man in relatively good health. I don’t smoke or drink, and I have a vegetarian diet. I exercise moderately, and I am not overweight. About 30 years ago, I ...

Throughout history, people have had to find ways to cope with varying environmental conditions. Whether they lived in a hot or cold climate or had access to plentiful or limited water, they adapted ...

Is it hot in here or is it just you? Naturally “running hot” or “running cold” has been the center of debates in households and offices since the advent of air conditioning, as battles over ...

Researchers performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for ...