The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

A new genetic mapping strategy reveals how entire networks of genes work together to cause disease, filling in the missing links left by traditional genetic studies. The technique could transform how ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate ...