The work addresses a persistent limitation in experimental diabetes therapies. In Type 1 diabetes, insulin producing islet ...

Forming sensory organs requires complicated interactions between numerous cell types. Building these tissues in a dish from human stem cells helps researchers understand how they develop over time and ...

When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are ...

The team of researchers led by Prof. Kristian Franze found that increasing tissue stiffness induces the expression of chemical signals that are typically absent in those regions. Semaphorin 3A is one ...

Researchers at Masaryk University, Czech Republic, have innovated a technique to track bone development, growth dynamics and healing in a mouse model. In their paper, "Spatiotemporal monitoring of ...

Tissue engineering is an interdisciplinary field that combines principles from engineering, biology, and materials science to develop biological substitutes that restore, maintain, or improve tissue ...

Adipose tissue is an underappreciated and misunderstood organ. Capable of more than doubling in mass and then returning to baseline, 1 white adipose tissue (WAT) continues to play an essential role in ...

Traditional-tissue engineering approaches (Panel A) seed cells onto a three-dimensional biomaterial scaffold that serves as a framework for new tissue development (i). The scaffold degrades as new ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead ...

A new type of tissue model that more accurately mimics the architecture of the liver could help develop drugs to treat MASLD.