The use of base editing to generate universal off-the-shelf CAR T cells induced durable remissions -- up to 36 months in one ...

Neoadjuvant FOLF(IRIN)OX Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Multicenter Randomized Noncomparative Phase II Trial (PANACHE01 FRENCH08 PRODIGE48 study) The aim of this open-label, ...

Organ transplants save lives, but unfortunately rejection is a key hurdle. Now scientists have demonstrated a potential new way to prime a recipient’s immune system to accept a transplanted organ, by ...

Younger patients with relapsed MDS may benefit from DLI post-stem cell transplant, improving overall survival rates. DLI is associated with graft-versus-host disease, but its impact on prognosis is ...

A recent study published in Nature Immunology demostrates that durable asthma remission can be achieved with engineered and long-lived chimeric antigen receptor (CAR) T-cell treatment in mice. Study: ...

An infusion of stem cells could help restore proper drainage for fluid-clogged eyes at risk for glaucoma. That's the upshot of a study led by a Veterans Affairs and University of Iowa team.

An intracoronary infusion of stem cells after PCI may benefit some STEMI patients as an adjunctive treatment in reducing the incidence of heart failure (HF), according to results from the ...

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a critical therapeutic strategy for treating conditions such as hematological malignancies, bone marrow failure syndromes, and ...

Regulatory T cells (Tregs) play a crucial role in maintaining a balanced immune system and safeguarding against chronic inflammatory diseases and autoimmune conditions. Scientists have long speculated ...

Encouraging Results Unlike bypass surgery, the stem cell procedure did not require a long recovery period. After the stem cell infusions, doctors followed Jones, Dearing, and 18 other patients in the ...