Understanding the mechanisms through which multicellular organisms regulate cell, organ and body growth is of relevance to developmental biology and to research on growth-related diseases such as ...
Two independent papers identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target. Two independent papers in the August 15th issue of Genes & Development identify the ...
The Tsc1/2 complex inactivates Rheb. A mutation in Tsc2 results in Rheb activation, inducing neuron morphological defects and dysfunctions. These abnormalities promote memory impairment in TSC mice.
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target. The first paper, from Dr. Pier Paolo Pandolfi (BIDMC ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results