The year 2015 has seen great progress in the renal fibrosis field, as key studies began to build a consensus on the importance of epithelial-to-mesenchymal transition, cell cycle arrest, and defective ...

Urea transporter (UT) proteins facilitate the passive transport of urea driven by a concentration gradient across the cell plasma membrane in some kidney and extrarenal cells The kidney expresses ...

In patients with diabetic nephropathy, glomerulopathy is an important renal structural change. The kidney consists of four basic tissue types: vessels, glomeruli, tubules, and interstitium. Each of ...

Eleven of 13 patients with far advanced chronic renal disease of diverse etiologies were found to have urine that remained hypotonic to plasma in spite of the administration of a supramaximal dose of ...

Niigata, Japan - The gold standard test for predicting the onset of diabetic kidney disease is albuminuria. However, detecting albuminuria alone has limited sensitivity and specificity in end-stage ...

Microscopical examination of the kidneys of patients with sickle-cell disease subjected to nephrectomy has revealed changes occurring principally in the area of the medulla. The changes included ...

Polycystic kidney disease is a painful disorder. In this condition, clusters of non-cancerous fluid-filled sacs, called cysts, form in the kidneys. A person suffering from this condition experience ...