T-cell therapies work well for blood cancers, but they come with caveats—a major one being that they’re cumbersome and expensive to tailor to a patient’s specific cancer type. On top of that, the ...

Chimeric antigen receptor (CAR) T cell therapy is a promising immunotherapy against cancer. The idea is to fortify a person’s immune system to fight its own battle by boosting T cells with the ability ...

Researchers publish the three-dimensional structure of the B cell antigen receptor, shedding new light on its composition The surface of B cells is covered with antigen receptors with which they ...

In a recent study published in the journal Nature, researchers from the United States of America developed the synthetic intramembrane proteolysis receptor (SNIPR) architecture to activate engineered ...

However, the measurement of sIL-2R is simple compared to the complex story behind this biomarker that has become so central to the study of immune-mediated disease. Why measure soluble interleukin-2 ...

Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity. GLP-1 receptor ...

The odor receptors in the nose are not distributed at random but organized in a precise spatial pattern, two new studies reveal. By Emily Anthes Over the last century, scientists have mapped several ...

Serotonin receptor agonists are a group of medications that activate the serotonin receptors in the central nervous system. A low serotonin level can lead to difficulty sleeping, depression, anxiety, ...

The surface of B cells is covered with antigen receptors with which they recognize invading pathogens such as bacteria and viruses. When a B cell receptor binds to an antigen, that is, to a foreign ...