When analyzing these pairs, researchers identified patterns between the extracellular and intracellular signals. They then trained a deep learning model to predict what the intracellular signals ...

Intracellular Delivery via EV-based Approach (IDEA) was designed to efficiently package and deliver non-fused intracellular proteins to cytoplasmic or nuclear compartments to be functional. As a ...

Extracellular vesicles (EVs) are tiny bubbles released by cells, acting as cargo vessels through which cells exchange signals and thus communicate. A paper has demonstrated that this form of cellular ...

New research from scientists at the Karolinska Institutet in Sweden and their collaborators elsewhere describes a way of improving extracellular vesicles’ ability to transport things like therapeutic ...

A novel method for deforming cells mechanically in viscoelastic fluids to enable high efficiency, high viability and high throughput intracellular delivery. Medical research has made incredible ...

Researchers from Singapore University of Technology and Design (SUTD) have leveraged their expertise in microfluidics to develop a novel method for deforming cells mechanically to facilitate ...

Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not even close. Senescence is the loss of a cell’s power to divide and grow, thus ...

Intracellular retention of TCRαβ/CD3 and CD7 to generate novel allogeneic CAR-T cells targeting CD7 for treating T-cell malignancies. Non-clinical evaluation of NT-112, an autologous T cell product ...