Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

In a recent study posted to bioRxiv *, researchers performed an analysis of molecular variance (AMOVA) in 59 haplotypes of the interferon (IFN)-alpha (α) /beta (β) receptor (IFNAR) gene, departing ...

Forbes contributors publish independent expert analyses and insights. William A. Haseltine, Ph.D., covers genomics and regenerative medicine Discussions of innate immunity typically focus on the ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. The possible FDA approval of a drug targeting the ...

Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: a pilot study. Forty-four patients were treated.

Deficiency of ubiquitin-specific peptidase 18 (USP18) is a severe type I interferonopathy. USP18 down-regulates type I interferon signaling by blocking the access of Janus-associated kinase 1 (JAK1) ...

Besremi is a monopegylated, long-acting interferon, which exhibits its cellular effects in the bone marrow in polycythemia vera. The Food and Drug Administration (FDA) has approved Besremi ® ...

A randomized double-blind cross-over patient preference study of pazopanib versus sunitinib in treatment-naive locally advanced or metastatic renal cell carcinoma (mRCC). Background: Bevacizumab + ...

Interferon therapies are well established as treatment options for some types of cancer, but they have not been used to treat cancers characterized by the overproduction of blood cells. The FDA has ...

PALO ALTO, Calif., Aug. 20, 2019 /PRNewswire/ -- Eiger BioPharmaceuticals, Inc. (Nasdaq: EIGR), focused on the development and commercialization of targeted therapies for rare and ultra-rare diseases, ...