Adenosine deaminase acting on RNA 1 (ADAR1) catalyses adenosine-to-inosine editing, often at non-coding regions of mRNAs. Mutations in ADAR1 cause Aicardi–Goutières syndrome (AGS), which is a ...

During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or ...

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of ...

Interferon therapies are well established as treatment options for some types of cancer, but they have not been used to treat cancers characterized by the overproduction of blood cells. The FDA has ...

Treatment of COVID-19 with interferon beta-1b — even for just a few days, a much shorter period than is commonly used for maintenance in multiple sclerosis (MS), for example — is associated with ...

In the body, macrophage memory formation depends on a signaling molecule, or cytokine, known as interferon gamma. During an initial immune response, interferon gamma prompts macrophages to unwrap ...

Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

In 1980, TIME Magazine wrote about interferon as the “if” drug for cancer. Promising studies sparked widespread hope around the potential of the interferon to treat cancer, only if it could deliver ...

A new drug quashes all coronavirus variants. But regulatory hurdles and a lack of funding make it unlikely to reach the U.S. market anytime soon. By Benjamin Mueller Over the past year, America’s ...