The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...
Takeaway 3: The Alcohol-to-Amide Shortcut The team extended their logic to create a "one-pot" enzymatic cascade that starts from broadly available aliphatic alcohols. This chemoenzymatic strategy is ...
The Beckmann rearrangement is a pivotal transformation in organic synthesis, enabling the conversion of ketoximes to amides via a nitrogen migration process. Over recent decades, advancements in ...
Chemists from HSE University and the Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences (INEOS RAS) have developed a new method for synthesising amides, essential ...
A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...
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