Dr. Sandeep Kunwar explained that getting drugs into the brain is a major hurdle for glioblastoma, as the blood-brain barrier blocks most treatments. Dr. Sandeep Kunwar, a neurosurgeon and professor ...
A new study describes a gene therapy strategy that uses the brain's own glymphatic transport system to distribute engineered viral vectors throughout the brain.
Blood-brain barrier drug delivery reached a landmark: the FDA’s March 2026 accelerated approval of Denali Therapeutics’ ...
A new study found that SSRIs may be able to help other drugs cross the blood-brain barrier. The findings could aid the delivery of drugs for conditions like dementia. The corresponding study was ...
Scientists developed a human pancreatic cancer fibrotic barrier 3D cell-culture model to assess treatments for pancreatic ductal adenocarcinoma. By targeting the ROCK2 pathway, they achieved a notable ...
Triple-negative breast cancer—the most aggressive breast cancer subtype—has a high propensity for brain metastases, with ...
Oligonucleotide therapeutics, including antisense oligonucleotides and small interfering ribonucleic acid (RNA), have emerged as powerful tools for regulating gene expression and treating neurological ...
African scientists have developed a nanoscale drug delivery system to treat pericarditis, a drug-resistant and lethal tuberculosis (TB). The scientists' system can breach the heart's protective ...
Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies.