A new study in Nature has mapped, at atomic resolution, how the enzyme DICER slices precursor microRNAs at exactly the right ...

A research team from The Hong Kong University of Science and Technology (HKUST) has made an advance in understanding the molecular machinery of RNA silencing. The team uncovered how the human enzyme ...

How an enzyme, appropriately named DICER, cuts double-stranded RNA to produce short sections of RNA that regulate genes has been revealed. Small snippets of RNAs can turn off genes, stopping them from ...

Sequence motifs and cleavage site specificity of DCL1 and other RNase III enzymes. (a) The GHR motifs define the DCL1 cleavage site. (b) Sequence motifs recognized by DCL1, Dicer, and Drosha, with ...