Compared to a phenotype considered healthy — having low adiposity and a high skeletal muscle index (SMI) — a phenotype with low adiposity and low SMI was associated with approximately 3-fold increased ...

The first-line treatment options for advanced and metastatic non-clear cell renal cell carcinoma (RCC) are growing, and various long-term updates on phase II trials were presented at the American ...

Gaining weight during adulthood and greater cumulative exposure to excess body weight raises the risk for overall, aggressive, fatal, and clear cell RCC. Interestingly, a reduction in BMI of at least ...

Stage 3 RCC involves tumor growth beyond the kidney, affecting nearby tissues or lymph nodes, but not distant organs. Diagnosis includes imaging, biopsy, and molecular testing to guide treatment ...

CAR T-cell therapy is being adapted for clear cell renal cell carcinoma, targeting CAIX and CD70 to improve efficacy and safety. Early trials like COBALT-RCC and TRAVERSE show promising disease ...