Pore-forming toxins (PFTs) are a diverse class of proteins capable of disrupting cell membranes through the formation of transmembrane channels. These molecular machines play a central role in both ...
The authors argue that many otherwise unrelated allergens and venoms carry pore-forming proteins, so perforation may explain why diverse stimuli provoke similar airway inflammation. Written for you by ...
Future Microbiol. 2013;8(1):73-84. Work in the Mulvey laboratory is supported by NIH grants AI095647, AI090369 and AI088086. TJ Wiles was funded by NIH Genetics Training Grant T32-GM007464. The ...
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