Health And Pharma

Pan-Cancer Analysis: ALK Mutation May Help Identify Tumors More Likely to Respond to Immunotherapy

A pan-cancer analysis of 2,930 patients across 11 tumor types found that ALK mutation was associated with significantly ...

Turning immune cells into tumor allies: A cancer cell protein can reprogram frontline defenders

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...
Frontiers

Overcoming Resistance to Immune Checkpoint Inhibitors: Mechanisms and Strategies in Cancer Therapy

This Research Topic is one volume within the series "The Future of Checkpoint Immunotherapy: New Roads Ahead". Please see the ...
Frontiers

Biomarkers, Mechanisms, and Therapeutic Strategies of Immune Checkpoint Blockade for Cancers

Immune checkpoint blockade (ICB) has reshaped modern immunotherapy by unleashing antitumor immune responses through targeting inhibitory immune checkpoints ...
Medscape

Can Dual Immunotherapy Replace Surgery in Gastric Cancer?

A small Italian study suggests a way to safely reduce gastrectomy rates in microsatellite instability-high disease.
ascopubs.org

Pathologic findings and clinical outcomes after immune checkpoint blockade in renal cell carcinoma patients undergoing deferred consolidative nephrectomy.

Integrative genomic landscape of germline exome alterations in renal cell carcinoma, unclassified with medullary phenotype. This is an ASCO Meeting Abstract from the 2026 ASCO Genitourinary Cancers ...