Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...

Gene Regulatory Networks (GRNs) reveal how genes regulate each other, offering insights into complex biological systems. Traditional GRN inference, based on bulk RNA sequencing, reflects average gene ...

The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom ...

When Dr. Ambroise Wonkam walked into a panel on medical genetics out of curiosity, he had no idea it would shape the course of his career. Born in Cameroon, Wonkam has dedicated his career to studying ...

Genetic carriers for sickle cell disease have higher risks of blood clots across diverse ancestries Study finds that sickle cell trait is prevalent among diverse human populations Date: September 12, ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

A new study reveals that habitat fragmentation can lead to sudden "tipping points" where a species' genetic health ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

CRISPR gene drives bias inheritance in pests, advancing population-level control while raising questions about resistance and ...