Our fat cells, called adipocytes, do more than just store extra weight. They play a key role in managing the body's energy. Adipocytes accumulate fat in the form of lipid droplets that the body can ...

Researchers have found a possible explanation as to why higher breast density and older age increase the risk of breast cancer. In an innovative study, researchers at the Turku Bioscience Centre, ...

In a recent preclinical study published in the Journal of Clinical Investigation, researchers in the United States of America investigated the role of the transcription factor KLF15 (short for Kruppel ...

Researchers led by the University of California, San Francisco (UCSF), report a new approach that deprived tumors of nutrition in cancer models, and may one day lead to a new approach that can be ...

Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell Medicine investigators. In the study, published ...

Skin fibrosis is an often-painful condition wherein the skin thickens and hardens, making it difficult to move. And with no effective treatments currently available, patients are left with few avenues ...

The common forms of type 2 diabetes are caused by a constellation of genetic and epigenetic factors and molecular changes related to diet; lifestyle, including lack of exercise and sleep; ...

Brown adipose tissue (BAT) dissipates energy as heat. In doing so, brown fat serves as a biological heater in humans—keeping newborns warm, and in adults, brown fat activation positively correlates ...

Blockbuster anti-obesity drugs like Ozempic and Wegovy have become household names in the past few years. They work by activating the glucagon-like peptide 1 receptor (GLP-1R) to stimulate insulin ...

Northwestern Medicine scientists led by Joseph Bass, MD, Ph.D., the Charles F. Kettering Professor of Endocrinology and ...