Eric Dane shared his journey with his ALS diagnosis, saying he maintains a positive outlook as he continues acting despite physical challenges.

Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

Actor Eric Dane is opening up about living with ALS. In his first television interview since revealing he has amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s Disease, Dane, 52, recalled the symptoms that led to discovering his diagnosis about a year and a half ago.